Lactylation: a metabolic sensor for faithful mitosis
Nov. 06, 2026
Dr. Di Zhang published a paper in Nature Metabolism.
Tumour cells preferentially rely on aerobic glycolysis to support rapid proliferation. In this issue of Nature Metabolism, Zhu et al. reveal that lactate, a metabolite generated by glycolysis, promotes faithful mitosis in tumour cells through protein lactylation.
Original Link: https://www.nature.com/articles/s42255-026-01649-y