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邓兴旺
邮  箱: deng(AT)pku.edu.cn
职  称:
教授
传  真: 62751076
办公室地址: 北京市海淀区颐和园路5号,北京大学,王克桢楼,100871
实验室电话: 62759987
实验室地址: 北京市海淀区颐和园路5号,北京大学,王克桢楼,100871
个人简历
个人介绍文字
  邓兴旺,博士,教授,博士生导师,美国科学院院士,中组部“千人计划”引进高层次人才。曾任耶鲁大学冠名终身教授(Daniel C. Eaton Professor)。1989年于美国加州大学伯克利分校获得博士学位,1992年开始在美国耶鲁大学建立实验室,任助理教授;1995年起任该校副教授,2001年起任该校终身正教授。其领导的研究团队迄今在《细胞》、《科学》和《自然》顶级刊物上发表14篇论文,在国际刊物上共发表304篇学术论文。2003年成为国际植物分子生物学会Kumho奖的唯一获奖者。2000年起担任北京大学-耶鲁大学植物分子遗传及农业生物技术联合中心主任,2010年入选“千人计划”,2013年入选美国科学院院士,2014年全职回北京大学工作。
教育经历
1985.9-1989.4: 博士(Ph.D.),美国,加州大学伯克利分校,植物生物学
1982.9-1985.7: 硕士(MS),中国,北京大学,植物生理学
1978.9-1982.7: 学士(BS),中国,北京大学,生物学
工作经历
2014.10-至今: 筹备小组组长,中国,北京大学现代农学院(筹)
2014.7.1-至今: 讲席教授(University Endowed Professor),中国,北京大学生命科学学院
2000.7-2014.6.30: 长江讲座教授(兼职) (Cheung Kong Chair Professor),中国,北京大学生命科学学院
2003.5-2014.6.30: 冠名终身教授(Daniel C. Eaton Professor),美国,耶鲁大学分子细胞和发育生物学系
2001.7-2014.6.30: 终身教授(Full Professor),美国,耶鲁大学分子细胞和发育生物学系
2000.10-至今: 主任(兼职) (Director),中国,北大-耶鲁植物遗传学和农业生物技术联合研究中心
2003-2008: 共同所长(兼职) (Director),中国,北京生命科学研究所
1998.7-2001.6: 终身职副教授(Associate Professor with tenure),美国,耶鲁大学分子细胞和发育生物学系
1995.7-1998.6: 副教授(Associate Professor with term),美国,耶鲁大学分子细胞和发育生物学系
1992.1-1995.6: 助理教授(Assistant Professor),美国,耶鲁大学分子细胞和发育生物学系
1989.5-1991.12: 博士后(Postdoc),美国,加州大学伯克利分校、美国农业部植物基因研究中心,植物分子生物学
社会服务工作
美国植物生理学家协会(American Society of Plant Physiologists)会员
美国科学发展促进会 (American Society for the Advancement of Science)会士
荣誉奖励
2013年: 当选为“美国科学院院士”( Elected member of US National Academy of Sciences)
2013年: 当选为“美国科学促进协会会士”(Elected fellow of American Association for Advancement of Science)
2003年: 获国际植物分子生物学学会(ISPMB)最重要奖项“The Kumho Science International Award”(2003)
1995年: 获“美国总统青年教师奖”(Presidential Faculty Fellow Award)

学术任职
2011年植物光生物学国际研讨会(The 2011 International Symposium of Plant Photobiology)组织者
第18届国际拟南芥研究大会(The 18th International Conference on Arabidopsis Research)组织者、主席(2007年)
The Arabidopsis Information Research (TAIR) 顾问委员会成员(2006-2008年)
Multinational Arabidopsis Research Committee主席(2007-2008年)
Multinational Arabidopsis Research Committee共同主席(2006-2007年)
North American Arabidopsis Research Steering Committee主席(2007-2008年)
North American Arabidopsis Research Steering Committee成员(2004-2008年)
Ohio State Arabidopsis Stock Center科学顾问委员会成员(2003-2006年)
MPI(德国马普研究院)for Plant Breeding Research科学顾问委员会成员(2003-2008年)
Scientific Review Group Member for Samsbury Laboratory成员(2003年)
杂志任职
“Plant Cell” 期刊编委(2008年至2014年)
“Annual Review of Plant Biology” 期刊编委(2010-2012年)
“Plant Journal” 期刊编委(2000-2005年)
“Molecular Plant” 期刊顾问委员会成员(2006年至今)
“Journal of Integrated Plant Biology” 期刊编委(2004年至今)
“Plant Molecular Biology” 期刊编委(1998年至今)
“Genes to Cell” 期刊编委(2000年至今)
书籍编撰
(I) 专著
1. Karplus, V. J., and Deng, X.W. (2007). Agricultural Biotechnology in China: Origins and Prospects (a book with 10 chapters). Forwarded by Norman E. Borlaug. Published December 7, 2007 by Springer.
(II) 书籍章节
13. He, G., and Deng X.W. (2013). Chromatin and gene expression mechanisms in hybrids. Chapter 20 in Hybrid and Polyploid Genomics. John Wiley & Sons, Inc.: 323-333.
12. Li, J., Li, G., Wang, H., and Deng, X.W. (2011). Phytochrome signaling mechanisms. Arabidopsis Book 9: e0148.
11. Yanagawa, Y., Feng, S., and Deng, X.W. (2005). Light control of plant development: a role of the ubiquitin/proteasome-mediated proteolysis. Chapter 29 in Light Sensing in Plants, pp. 253-260. Eds: Wada, M., Shimazaki, K., and Lino, M. Springer.
10. Li, L., Wang, X., Li, X., Su, N., Stolc, V., Han, B., Li, J., Xue, Y., Wang, J., and Deng, X.W. (2004). Toward genome-wide transcriptional analysis in rice using MAS oligonucleotide tiling-path microarrays. In Rice Is Life: Scientific Perspectives For The 21st Century. Eds: Toriyama K., Heong, K. L. and Hardy, B. Proceedings of the World Rice Research Conference.
9. Wang, H., and Deng, X.W. (2002). Phytochrome signaling mechanisms. In The Arabidopsis Book, Eds. Somerville, C. R., and Meyerowitz, E. M., American Society of Plant Biologists.
8. Schwechheimer, C., and Deng, X.W. (2002). FPLC Gel Filtration. In Arabidopsis-A Laboratory Manual pp. 226-228, Eds: Weigel, D., and Glazebrook, J. Cold Spring Harbor Laboratory Press.
7. Schwechheimer, C., and Deng, X.W. (2002). Studying protein-protein interactions with the yeast two-hybid system. Chapter 9 in Molecular Plant Biology: A practical Approach, volume II, pp. 173-198. Eds: Philip M. G. and Chris B. Oxford University Press.
6. Habashi, J., and Deng, X.W. (2002). Nondenaturing Gel Electrophoresis of Proteins. In Arabidopsis-A Laboratory Manual. pp. 228-233, Eds: Weigel, D., and Glazebrook, J. Cold Spring Harbor Laboratory Press.
5. Chamovitz, D.A., and Deng, X.W. (1998). Molecular approaches to biochemical purification: the COP9 complex paradigm. NATO ASI series, vol. H104, 83-91.
4. Kwok, S. F., and Deng, X.W. (1996). The role of he pleiotropic Arabidopsis COP/DET/FUS genes in repression of photomorphogenic development in darkness. In Current Topics in Plant Physiology: an american Society of Plant Physiologists Series on [regulation of plant growth and development by light] vol. 17 pg.134-143
3. Deng, X.W., and Gruissem, W. (1994). Chloroplast run-on transcription: determination of the transcription activity of chloroplast genes. A chapter on a published laboratory manual based on a COLD SPRING HARBOR COURSE.
2. Melis, A., and Deng, X.W. (1987). The physiological significance of thylakoid membrane protein phosphorylation. In Progress in Photosynthesis Research, Eds: Biggins, J. Vol. II (2):257 260. Springer.
1. Gruissem, W., Deng, X.W., Jones, H., Stern, D, Tonkyn, J., and Zurawski, G. (1987). Transcriptional and post transcriptional regulation of chloroplast gene expression. In Structure and Function of Plant Genome, pp.135 148, Eds: Von Wettstein D., Chua, N. H. Plenum Press, New York.
(III) 书籍中译本
2. Published in Chinese in June 2006. Mechanisms in Plant Development. Eds: Ottoline Leyser, and Stephen Day. Wiley-Blackwell, Oxford. 2002 version.
1. Published in Chinese in February 2004. Biochemistry & Molecular Biology of Plants. Eds: Bob Buchanan, Wilhelm Gruissem, and Russell Jones. American Society of Plant Physiologists, Rockville, MD, USA. 2002 version.
科研领域描述
  邓兴旺课题组以拟南芥、水稻等为研究对象,主要从事植物光信号转导、非编码RNA、植物杂种优势分子机理和分子设计育种领域的研究工作。本课题组目前有教授1人,副研究员4人,博士后、技术员和博士研究生多名,实验室建有配套齐全的植物基因组学、分子生物学、生物信息学等研究平台,具有长期的植物基因组学及分子生物学研究经验。实验室具体研究方向如下:
  1. 植物光形态建成的分子机理
  光是对于植物发育最重要也是最基本的生长信号。本实验室多年来以拟南芥为模式植物,通过遗传筛选获得了一系列光形态建成的抑制因子COP/DET/FUS。它们的突变体在暗中可以完成不同程度的光形态建成。多年的研究结果表明,这些因子在植物体内可以形成三个复合体并通过参与或调节泛素化途径来调控光信号传导。目前,在此基础上,我们将继续综合运用遗传学、生物化学、分子生物学、细胞生物学等实验手段,进一步解析光形态建成中的信号传导通路。
  2. 植物非编码RNA功能分析
  非编码RNA是直接以RNA形式行使生物学功能的核糖核酸群体的总称。本实验室通过独特的分离方式以及深度测序技术,在拟南芥和水稻全基因组中对50-300核苷酸长度的非编码RNA进行了注释,并结合分子生物学,生物化学及细胞生物学等手段,探讨:小核仁RNA在拟南芥生长发育中的作用机理;非编码RNA参与拟南芥光形态建成中的分子机理;由较长非编码RNA产生的小分子RNA在拟南芥及水稻发育调控中的作用机理。
  3. 植物杂种优势形成的分子机理
  杂种优势是自然界普遍存在的一种复杂生物学现象,在农业生产中得到了广泛的应用。但是,对于杂种优势形成的分子遗传机理迄今尚未阐述清楚。本实验室以水稻、玉米和拟南芥为研究对象,采用高通量测序技术,对具有不同优势程度的杂交组合进行全基因组基因差异表达分析,进一步分析造成这种差异表达的基于顺、反式调控的遗传机制,以及基于DNA甲基化、组蛋白修饰和非编码RNA的表观遗传机制。并通过整合杂种优势的经典遗传学假说,在分子水平上解析杂种优势形成的机理,为在农业生产上更好地应用杂种优势现象进行杂交育种提供理论指导。
  4. 水稻功能基因组与分子设计育种
  传统水稻育种依赖于育种家的经验,需要从大量的水稻杂交后代中挑选优良水稻株系,效率较低。随着基因组学与分子生物学技术的进步,在育种过程中对调控特定性状的基因位点进行跟踪成为了可能。我们通过利 用大量的水稻全基因组重测序信息,创制了水稻高密度单核苷酸多态性(SNP)芯片,并将其应用于水稻育种,从而使得水稻育种成为可以精确设计与控制的过程。我们创制的芯片及相应的设计流程大大提高了水稻育种效率,加快了培育高产、优质、多抗水稻品种的进程。
代表性论文
304 Ling, J.J., Li, J., Zhu, D. and Deng, X.W. (2017). Noncanonical role of Arabidopsis COP1/SPA complex in repressing BIN2-mediated PIF3 phosphorylation and degradation in darkness. Proc Natl Acad Sci U S A doi:10.1073/pnas.1700850114.
303 Zhu, P., Wang, Y., Qin, N., Wang, F., Wang, J., Deng, X.W., and Zhu, D. (2016). Arabidopsis small nucleolar RNA monitors the efficient pre-rRNA processing during ribosome biogenesis. Proc Natl Acad Sci U S A 113, 11967-11972.
302 Chang, Z., Chen, Z., Wang, N., Xie, G., Lu, J., Yan, W., Zhou, J., Tang, X., and Deng, X.W. (2016). Construction of a male sterility system for hybrid rice breeding and seed production using a nuclear male sterility gene. Proc Natl Acad Sci U S A 113, 14145-14150.
301 Li, K., Yu, R., Fan, L.M., Wei, N., Chen, H., and Deng, X.W. (2016). DELLA-mediated PIF degradation contributes to coordination of light and gibberellin signalling in Arabidopsis. Nat Commun 7, 11868.
300 Shi, H., Shen, X., Liu, R., Xue, C., Wei, N., Deng, X.W., and Zhong, S. (2016). The Red Light Receptor Phytochrome B Directly Enhances Substrate-E3 Ligase Interactions to Attenuate Ethylene Responses. Dev Cell 39, 597-610.
299 Xu, D., Jiang, Y., Li, J., Lin, F., Holm, M., and Deng, X.W. (2016). BBX21, an Arabidopsis B-box protein, directly activates HY5 and is targeted by COP1 for 26S proteasome-mediated degradation. Proc Natl Acad Sci U S A 113, 7655-7660.
298 Yan, W., Chen, Z., Lu, J., Xu, C., Xie, G., Li, Y., Deng, X.W., He, H., and Tang, X. (2016). Simultaneous Identification of Multiple Causal Mutations in Rice. Frontiers in plant science 7, 2055.
297 Yu, R., Yan, W., Liang, M., Dai, X., Chen, H., Sun, Y., Deng, X.W., Chen, X., He, H., and Chen, L. (2016). Exploring the genetic characteristics of 93-11 and Nipponbare recombination inbred lines based on the GoldenGate SNP assay. Sci China Life Sci 59, 700-708.
296 Sun, N., Wang, J., Gao, Z., Dong, J., He, H., Terzaghi, W., Wei, N., Deng, X.W. and Chen H. (2016). Arabidopsis SAURs are critical for differential light regulation of the development of various organs. Proc Natl Acad Sci U S A pii: 201604782.
295 Yan, J., Lv, S., Hu, M., Gao, Z., He, H., Ma, Q., Deng, X.W., Zhu Z. and Wang X. (2016). Single-Molecule Sequencing Assists Genome Assembly Improvement and Structural Variation Inference. Mol Plant doi: 10.1016/j.molp.2016.04.002.
294 Yang, M., Huang, H., Zhang, C., Wang, Z., Su, Y., Zhu, P., Guo, Y. and Deng, X.W. (2016). Arabidopsis atypical kinase ABC1K1 is involved in red light-mediated development. Plant Cell Rep 35(6): 1213-1220.
293 Xu, D., Zhu, D. and Deng, X.W. (2016). The role of COP1 in repression of photoperiodic flowering. F1000Res 5.
292 Yu, Y., Wang, J., Shi, H., Gu, J., Dong, J., Deng, X.W. and Huang R. (2016). Salt stress and ethylene antagonistically regulate nucleocytoplasmic partitioning of COP1 to control seed germination. Plant Physiol pii: pp.01724.2015.
291 Shi, H., Liu, R., Xue, C., Shen, X., Wei, N., Deng, X.W. and Zhong S. (2016). Seedlings Transduce the Depth and Mechanical Pressure of Covering Soil Using COP1 and Ethylene to Regulate EBF1/EBF2 for Soil Emergence. Curr Biol 26(2): 139-149.
290 Ma, L., Tian, T., Lin, R., Deng, X.W., Wang H. and Li G. (2016). Arabidopsis FHY3 and FAR1 Regulate Light-Induced myo-Inositol Biosynthesis and Oxidative Stress Responses by Transcriptional Activation of MIPS1. Mol Plant 9(4): 541-557.
289 Yang, M., Wang, X., Huang, H., Ren, D., Su, Y., Zhu, P., Zhu, D., Fan, L., Chen, L., He, G. and Deng, X.W. (2016). Natural variation of H3K27me3 modification in two Arabidopsis accessions and their hybrid. J Integr Plant Biol 58(5): 466-474.
288 Dutilleul, C., Ribeiro, I., Blanc, N., Nezames, C. D., Deng, X.W., Zglobicki, P., Palacio Barrera, A. M., Atehortua, L., Courtois, M., Labas, V., Giglioli-Guivarc'h, N. and Ducos, E. (2016). ASG2 is a farnesylated DWD protein that acts as ABA negative regulator in Arabidopsis. Plant Cell Environ 39(1): 185-198.
287 Zhou, D., Chen, W., Lin, Z., Chen, H., Wang, C., Li, H., Yu, R., Zhang, F., Zhen, G., Yi, J., Li, K., Liu, Y., Terzaghi, W., Tang, X., He, H., Zhou, S. and Deng, X.W. (2016). Pedigree-based analysis of derivation of genome segments of an elite rice reveals key regions during its breeding. Plant Biotechnol J 14(2): 638-648.
286 Huang, L., Zhang, H., Zhang, H., Deng, X.W. and Wei, N. (2015). HY5 regulates nitrite reductase 1 (NIR1) and ammonium transporter1;2 (AMT1;2) in Arabidopsis seedlings. Plant Sci 238: 330-339.
285 Xu, D., Lin, F., Jiang, Y., Ling, J., Hettiarachchi, C., Tellgren-Roth, C., Holm, M., Wei, N. and Deng, X.W. (2015). Arabidopsis COP1 SUPPRESSOR 2 Represses COP1 E3 Ubiquitin Ligase Activity through Their Coiled-Coil Domains Association. PLoS Genet 11(12): e1005747.
284 Zhu, L., Bu, Q., Xu, X., Paik, I., Huang, X., Hoecker, U., Deng, X.W. and Huq, E. (2015). CUL4 forms an E3 ligase with COP1 and SPA to promote light-induced degradation of PIF1. Nat Commun 6: 7245.
283 Dong, J., Terzaghi, W., Deng, X.W. and Chen H. (2015). Multiple photomorphogenic repressors work in concert to regulate Arabidopsis seedling development. Plant Signal Behav 10(3): e1011934.
282 Huang, H., Yang, M., Su, Y., Qu, L., and Deng, X.W. (2015). Arabidopsis Atypical Kinases ABC1K1 and ABC1K3 Act Oppositely to Cope with Photodamage Under Red Light. Mol Plant 8, 1122-1124.
281 Yang, L., Li, B., Zheng, X.Y., Li, J., Yang, M., Dong, X., He, G., An, C., and Deng, X.W. (2015). Salicylic acid biosynthesis is enhanced and contributes to increased biotrophic pathogen resistance in Arabidopsis hybrids. Nat Commun 6, 7309.
280 Li, K., Gao, Z., He, H., Terzaghi, W., Fan, L.M., Deng, X.W., and Chen, H. (2015). Arabi !E omorphogenesis in Part by Negatively Regulating DELLA Protein Abundance in Darkness. Mol Plant 8, 622-630.
279 Shi, H., Wang, X., Mo, X., Tang, C., Zhong, S., and Deng, X.W. (2015). Arabidopsis DET1 degrades HFR1 but stabilizes PIF1 to precisely regulate seed germination. Proc Natl Acad Sci U S A. 112, 3817-3822.
278 Zhang, H., Zhao, X., Li, J., Cai, H., Deng, X.W., and Li, L. (2014). MicroRNA408 is critical for the HY5-SPL7 gene network that mediates the coordinated response to light and copper. Plant Cell 26, 4933-4953.
277 Kim, S. H., Kim, H., Seo, K. I., Kim, S. H., Chung, S., Huang, X., Yang, P., Deng, X. W., and Lee, J. H. (2014). DWD HYPERSENSITIVE TO UV-B 1 is negatively involved in UV-B mediated cellular responses in Arabidopsis. Plant Mol Biol 86, 571-583.
276 Kim, S. H., Lee, J. H., Seo, K. I., Ryu, B., Sung, Y., Chung, T., Deng, X. W., and Lee, J. H (2014). Characterization of a Novel DWD Protein that Participates in Heat Stress Response in Arabidopsis. Mol Cells 37, 833-840.
275 Dong, J., Tang, D., Gao, Z., Yu, R., Li, K., He, H., Terzaghi, W., Deng, X. W. and Chen, H. (2014). Arabidopsis DE-ETIOLATED1 Represses Photomorphogenesis by Positively Regulating Phytochrome-Interacting Factors in the Dark. Plant Cell 26, 3630-3645.
274 Wang, L., Li, J., Zhou, Q., Yang, G., Ding, X. L., Li, X., Cai, C. X., Zhang, Z., Wei, H. Y., Lu, T. H., Deng, X. W. and Huang, X. H. (2014). Rare earth elements activate endocytosis in plant cells. Proc Natl Acad Sci U S A. 111, 12936-12941.
273 Chen, F., Li, B., Demone, J., Charron, J.B., Shi, X., and Deng, X.W. (2014). Photoreceptor partner FHY1 has an independent role in gene modulation and plant development under far-red light. Proc Natl Acad Sci U S A 111, 11888-11893.
272 Huang, X., Ouyang, X., and Deng, X.W. (2014). Beyond repression of photomorphogenesis: role switching of COP/DET/FUS in light signaling. Curr Opin Plant Biol 21C, 96-103.
271 Ouyang, X., Huang, X., Jin, X., Chen, Z., Yang, P., Ge, H., Li, S., and Deng, X.W. (2014). Coordinated photomorphogenic UV-B signaling network captured by mathematical modeling. Proc Natl Acad Sci U S A 111, 11539-11544.
270 Wang, Y., Fan, X., Lin, F., He, G., Terzaghi, W., Zhu, D., and Deng, X.W. (2014). Arabidopsis noncoding RNA mediates control of photomorphogenesis by red light. Proc Natl Acad Sci U S A 111, 10359-10364.
269 Xu, D., Lin, F., Jiang, Y., Huang, X., Li, J., Ling, J., Hettiarachchi, C., Tellgren-Roth, C., Holm, M., and Deng, X.W. (2014). The RING-Finger E3 Ubiquitin Ligase COP1 SUPPRESSOR1 Negatively Regulates COP1 Abundance in Maintaining COP1 Homeostasis in Dark-Grown Arabidopsis Seedlings. Plant Cell 26, 1981-1991.
268 Chen, F., Li, B., Li, G., Charron, J.B., Dai, M., Shi, X., and Deng, X.W. (2014). Arabidopsis Phytochrome A Directly Targets Numerous Promoters for Individualized Modulation of Genes in a Wide Range of Pathways. Plant Cell 26, 1949-1966.
267 Jin, D., Li, B., Deng, X.W., and Wei, N. (2014). Plant COP9 signalosome subunit 5, CSN5. Plant Sci 224, 54-61.
266 Huang, X., Yang, P., Ouyang, X., Chen, L., and Deng, X.W. (2014). Photoactivated UVR8-COP1 module determines photomorphogenic UV-B signaling output in Arabidopsis. PLoS Genet 10, e1004218.
265 Zhong, S., Shi, H., Xue, C., Wei, N., Guo, H., and Deng, X.W. (2014). Ethylene-orchestrated circuitry coordinates a seedling's response to soil cover and etiolated growth. Proc Natl Acad Sci U S A 111, 3913-3920.
264 Xu, D., Li, J., Gangappa, S.N., Hettiarachchi, C., Lin, F., Andersson, M.X., Jiang, Y., Deng, X.W., and Holm, M. (2014). Convergence of Light and ABA signaling on the ABI5 promoter. PLoS Genet 10, e1004197.
263 Xu, X., Paik, I., Zhu, L., Bu, Q., Huang, X., Deng, X.W., and Huq, E. (2014). PHYTOCHROME INTERACTING FACTOR1 Enhances the E3 Ligase Activity of CONSTITUTIVE PHOTOMORPHOGENIC1 to Synergistically Repress Photomorphogenesis in Arabidopsis. Plant Cell 26, 1992-2006.
262 Wang, Y., Wang, X., Deng, W., Fan, X., Liu, T.T., He, G., Chen, R., Terzaghi, W., Zhu, D., and Deng, X.W. (2014). Genomic features and regulatory roles of intermediate-sized non-coding RNAs in Arabidopsis. Mol Plant 7, 514-527.
261 Seo, K.I., Lee, J.H., Nezames, C.D., Zhong, S., Song, E., Byun, M.O., and Deng, X.W. (2014). ABD1 is an Arabidopsis DCAF substrate receptor for CUL4-DDB1-based E3 ligases that acts as a negative regulator of abscisic acid signaling. Plant Cell 26, 695-711.
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42 Chattopadhyay, S., Ang, L.H., Puente, P., Deng, X.W., and Wei, N. (1998). Arabidopsis bZIP protein HY5 directly interacts with light-responsive promoters in mediating light control of gene expression. Plant Cell 10, 673-683.
41 Ang, L.H., Chattopadhyay, S., Wei, N., Oyama, T., Okada, K., Batschauer, A., and Deng, X.W. (1998). Molecular interaction between COP1 and HY5 defines a regulatory switch for light control of Arabidopsis development. Mol Cell 1, 213-222.
40 von Arnim, A.G., Osterlund, M.T., Kwok, S.F., and Deng, X.W. (1997). Genetic and developmental control of nuclear accumulation of COP1, a repressor of photomorphogenesis in Arabidopsis. Plant Physiol 114, 779-788.
39 Torii, K.U., and Deng, X.W. (1997). The role of COP1 in light control of Arabidopsis seedling development. Plant Cell Environ 20, 728-733.
38 Deng, X.W., and Mei, Z. (1997). The higher plant thylakoid pigment-protein complexes migration and the reduction of light energy distribution between two photosystems. Scientia Sinica (series B) 4, 377-386.
37 Chamovitz, D.A., and Deng, X.W. (1997). The COP9 complex: a link between photomorphogenesis and general developmental regulation? Plant Cell Environ 20, 734-739.
36 Wei, N., and Deng, X.W. (1996). The role of the COP/DET/FUS genes in light control of arabidopsis seedling development. Plant Physiol 112, 871-878.
35 von Arnim, A., and Deng, X.W. (1996). A role for transcriptional repression during light control of plant development. Bioessays 18, 905-910.
34 Von Arnim, A., and Deng, X.W. (1996). Light control of seedling development. Annu Rev Plant Physiol Plant Mol Biol 47, 215-243.
33 Staub, J.M., Wei, N., and Deng, X.W. (1996). Evidence for FUS6 as a component of the nuclear-localized COP9 complex in Arabidopsis. Plant Cell 8, 2047-2056.
32 Staub, J.M., and Deng, X.W. (1996). Light signal transduction in plants. Photochem Photobiol 64, 897-905.
31 Puente, P., Wei, N., and Deng, X.W. (1996). Combinatorial interplay of promoter elements constitutes the minimal determinants for light and developmental control of gene expression in Arabidopsis. EMBO J 15, 3732-3743.
30 McNellis, T.W., Torii, K.U., and Deng, X.W. (1996). Expression of an N-terminal fragment of COP1 confers a dominant-negative effect on light-regulated seedling development in Arabidopsis. Plant Cell 8, 1491-1503.
29 Kwok, S.F., Piekos, B., Misera, S., and Deng, X.W. (1996). A complement of ten essential and pleiotropic arabidopsis COP/DET/FUS genes is necessary for repression of photomorphogenesis in darkness. Plant Physiol 110, 731-742.
28 Deng, X.W., and Melis, A. (1996). Phosphorylation of the light-harvesting complex II in higher plant chloroplasts: effect on photosystem II and photosystem I absorption cross section. Photochem Photobiol 13, 41-52.
27 Chamovitz, D.A., Wei, N., Osterlund, M.T., von Arnim, A.G., Staub, J.M., Matsui, M., and Deng, X.W. (1996). The COP9 complex, a novel multisubunit nuclear regulator involved in light control of a plant developmental switch. Cell 86, 115-121.
26 Chamovitz, D.A., Deng, X.W., and Lam, E. (1996). Light signaling in plants. Crit Rev Plant Sci 15, 455-478.
25 Torii, K.U., and Deng, X.W. (1995). Regulation of plant form: Identification of a molecule controlling cell expansion. Bioessays 17, 383-386.
24 McNellis, T.W., and Deng, X.W. (1995). Light control of seedling morphogenetic pattern. Plant Cell 7, 1749-1761.
23 Matsui, M., Stoop, C.D., von Arnim, A.G., Wei, N., and Deng, X.W. (1995). Arabidopsis COP1 protein specifically interacts in vitro with a cytoskeleton-associated protein, CIP1. Proc Natl Acad Sci U S A 92, 4239-4243.
22 Chamovitz, D.A., and Deng, X.W. (1995). The novel components of the Arabidopsis light signaling pathway may define a group of general developmental regulators shared by both animal and plant kingdoms. Cell 82, 353-354.
21 Wei, N., Kwok, S.F., von Arnim, A.G., Lee, A., McNellis, T.W., Piekos, B., and Deng, X.W. (1994). Arabidopsis COP8, COP10, and COP11 genes are involved in repression of photomorphogenic development in darkness. Plant Cell 6, 629-643.
20 Wei, N., Chamovitz, D.A., and Deng, X.W. (1994). Arabidopsis COP9 is a component of a novel signaling complex mediating light control of development. Cell 78, 117-124.
19 von Arnim, A.G., and Deng, X.W. (1994). Light inactivation of Arabidopsis photomorphogenic repressor COP1 involves a cell-specific regulation of its nucleocytoplasmic partitioning. Cell 79, 1035-1045.
18 McNellis, T.W., von Arnim, A.G., and Deng, X.W. (1994). Overexpression of Arabidopsis COP1 results in partial suppression of light-mediated development: evidence for a light-inactivable repressor of photomorphogenesis. Plant Cell 6, 1391-1400.
17 McNellis, T.W., von Arnim, A.G., Araki, T., Komeda, Y., Misera, S., and Deng, X.W. (1994). Genetic and molecular analysis of an allelic series of cop1 mutants suggests functional roles for the multiple protein domains. Plant Cell 6, 487-500.
16 Deng, X.W. (1994). Fresh view of light signal transduction in plants. Cell 76, 423-426.
15 Ang, L.H., and Deng, X.W. (1994). Regulatory hierarchy of photomorphogenic loci: allele-specific and light-dependent interaction between the HY5 and COP1 loci. Plant Cell 6, 613-628.
14 von Arnim, A.G., and Deng, X.W. (1993). Ring finger motif of Arabidopsis thaliana COP1 defines a new class of zinc-binding domain. J Biol Chem 268, 19626-19631.
13 Hou, Y., Von Arnim, A.G., and Deng, X.W. (1993). A New Class of Arabidopsis Constitutive Photomorphogenic Genes Involved in Regulating Cotyledon Development. Plant Cell 5, 329-339.
12 Wei, N., and Deng, X.W. (1992). COP9: a new genetic locus involved in light-regulated development and gene expression in arabidopsis. Plant Cell 4, 1507-1518.
11 Tonkyn, J.C., Deng, X.W., and Gruissem, W. (1992). Regulation of Plastid Gene Expression during Photooxidative Stress. Plant Physiol 99, 1406-1415.
10 Deng, X.W., and Quail, P.H. (1992). Genetic and phenotypic characterization of cop1 mutants of Arabidopsis thaliana. Plant J 2, 83-95.
9 Deng, X.W., Matsui, M., Wei, N., Wagner, D., Chu, A.M., Feldmann, K.A., and Quail, P.H. (1992). COP1, an Arabidopsis regulatory gene, encodes a protein with both a zinc-binding motif and a G beta homologous domain. Cell 71
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