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陈浩东

邮  箱: chenhaodong@pku.edu.cn

职  称:副研究员

实验室地址:北京市海淀区颐和园路5号,北京大学,王克桢楼,100871

  • 个人简介
  • 科研领域
  • 代表性论文

教育经历:

2003 - 2008 , 理学博士 , 生物技术 , 北京大学
2006 - 2008 , 交换学生 , 分子细胞发育生物学系 , 耶鲁大学
1999 - 2003 , 理学学士 , 生物技术 , 北京大学

荣誉奖励:

北京大学绿叶生物医药杰出青年学者奖,2016
北京大学优秀博士后 , 2010
北京大学优秀博士毕业生 , 2008

工作经历:

2010 - 至今 , 副研究员 , 北京大学
2008 - 2010 , 博士后 , 植物分子生物学 , 北京大学
      植物生长时刻受到周围环境的影响,地球环境中影响植物生长最重要的物理因子包括光和重力等。本课题组综合运用拟南芥与苔藓等研究体系,鉴定在光和重力信号感受或传递中发挥核心作用的因子并研究它们的工作机制,深入解析光和重力信号转导通路,为理解环境信号在植物生长发育中的作用以及改良相关农艺性状提供理论基础。
1. Wang, X., Yu, R., Wang, J., Lin, Z., Deng, Z., He, H., Fan, L., Deng, X.W., and Chen, H.* (2020). The asymmetric expression of SAUR genes mediated by ARF7/19 promotes the gravitropism and phototropism of plant hypocotyls. Cell Reports 31
2. Dong, J., Sun, N., Yang, J., Deng, Z., Lan, J., Qin, G., He, H., Deng, X.W., Irish V.F., Chen, H.,* and Wei, N.* (2019). TCP4 and PIF3 antagonistically regulate organ-specific light induction of SAUR16/50 to modulate cotyledon opening during de-etiolation in Arabidopsis. Plant Cell 31, 1155-1170.
3. Dong, J., Ni, W., Yu, R., Deng, X.W., Chen, H.,* and Wei, N. (2017). Light-dependent degradation of PIF3 by SCFEBF1/2 promotes a photomorphogenic response in Arabidopsis. Curr Biol 27, 2420-2430.
Highlighted by “news & views” of Nat Plants 3, 846–847 (2017)
4. Sun, N., Wang, J., Gao, Z., Dong, J., He, H., Terzaghi, W., Wei, N., Deng, X.W.,* and Chen, H.* (2016). Arabidopsis SAURs are critical for differential light regulation of the development of various organs. Proc Natl Acad Sci U S A 113, 6071-6076.
Highlighted by “Commentary” of Proc Natl Acad Sci U S A 113, 5774-5776 (2016)
5. Li, K., Yu, R., Fan, L.M., Wei, N., Chen, H.,* and Deng, X.W.* (2016). DELLA-mediated PIF degradation contributes to coordination of light and gibberellin signalling in Arabidopsis. Nat Commun 7, 11868.
Highlighted by “Spotlight” of Trends Plant Sci 21, 813-815 (2016)
6. Li, K., Gao, Z., He, H., Terzaghi, W., Fan, L.M., Deng, X.W.,* and Chen, H.* (2015). Arabidopsis DET1 represses photomorphogenesis in part by negatively regulating DELLA protein abundance in darkness. Mol Plant 8, 622-630.
7. Dong, J., Tang, D., Gao, Z., Yu, R., Li, K., He, H., Terzaghi, W., Deng, X.W., and Chen, H.* (2014). Arabidopsis DE-ETIOLATED1 represses photomorphogenesis by positively regulating phytochrome-interacting factors in the dark. Plant Cell 26, 3630-3645.
8. Chen, H., # Xie, W., # He, H., # Yu, H., # Chen, W., Li, J., Yu, R., Yao, Y., Zhang, W., He, Y., Tang, X., Zhou, F., Deng, X.W., and Zhang, Q. (2014). A high-density SNP genotyping array for rice biology and molecular breeding. Mol Plant 7, 541-553.
9. Chen, H.,* He, H., Zhou, F., Yu, H., and Deng, X.W.* (2013). Development of genomics-based genotyping platforms and their applications in rice breeding. Curr Opin Plant Biol 16, 247-254.
10. Chen, H.,# Huang, X.,# Gusmaroli, G., Terzaghi, W., Lau, O.S., Yanagawa, Y., Zhang, Y., Li, J., Lee, J.H., Zhu, D., and Deng, X.W. (2010). Arabidopsis CULLIN4-Damaged DNA Binding Protein 1 Interacts with CONSTITUTIVELY PHOTOMORPHOGENIC1-SUPPRESSOR OF PHYA Complexes to Regulate Photomorphogenesis and Flowering Time. Plant Cell 22, 108-123.
11. Chen, H., Shen, Y., Tang, X., Yu, L., Wang, J., Guo, L., Zhang, Y., Zhang, H., Feng, S., Strickland, E., Zheng, N., and Deng, X.W. (2006). Arabidopsis CULLIN4 forms an E3 ubiquitin ligase with RBX1 and the CDD complex in mediating light control of development. Plant Cell 18, 1991-2004.

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