Home /
QIAN, Weiqiang
Office Address: Wang Kezhen Building,Peking University, No.5 Yiheyuan Road, Haidian District,Beijing, P.R.China 100871
Lab Address: Wang Kezhen Building,Peking University, No.5 Yiheyuan Road, Haidian District,Beijing, P.R.China 100871
Lab Homepage: http://
Personal Homepage: http://
2011-2011, Postdoc. training, Purdue University
2009-2010, Postdoc. training, UC Riverside
2007-2009, Postdoc. training, Cornell University
2006-2007, Visiting student, Queens` University
2002-2007, Ph.D, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences
1998-2002, B.S, Beijing Normal University

Professional Experience
2013-Now, Assistant Professor, Peking University
2012-2013, Associate Investigator,Shanghai Center for Plant Stress Biology, Chinese Academy of Sciences

Representative Peer-Reviewed Publications
1. Sun L*., Jing Y*., Liu X*., Li Q*., Xue Z., Cheng Z., Wang D., He H., and Qian W. (2020) Heat stress-induced transposon activation correlates with 3D chromatin organization rearrangement in Arabidopsis. Nat. Commun. doi: 10.1038/s41467-020-15809-5. (*Contributed equally to this work)
2. Yuan W.*, Zhou J.*, Tong J.*, Zhuo W., Wang L., Li Y., Sun Q., and Qian W. (2019) ALBA protein complex reads genic R-loops to maintain genome stability in Arabidopsis. Sci. Adv. 5, eaav9040. (*Contributed equally to this work)
3. Wang X., Chen X., Sun L., and Qian W. (2019) Canonical Cytosolic Iron-Sulfur Cluster Assembly and Non-Canonical Functions of DRE2 in Arabidopsis. PLoS Genet 15, e1008094.
4. Li J.*, Liang W.*, Li Y., and Qian W. (2018). APURINIC/APYRIMIDINIC ENDONUCLEASE2 and ZINC FINGER DNA 3`-PHOSPHOESTERASE Play Overlapping Roles in the Maintenance of Epigenome and Genome Stability. Plant Cell 30, 1954-1970. (*Contributed equally to this work)
5. Li Y., Kumar S., and Qian W. (2018). Active DNA demethylation: mechanism and role in plant development. Plant Cell Rep. 37, 77-85.
6. Jing Y., Sun H., Yuan W., Wang Y., Li Q., Liu Y., Li Y., and Qian W. (2016). SUVH2 and SUVH9 couple two essential steps for transcriptional gene silencing in Arabidopsis. Mol. Plant 9, 1156-1167.
7. Wang X., Li Q., Yuan W., Cao Z., Qi B., Kumar S., Li Y., and Qian W. (2016). The cytosolic Fe-S cluster assembly component MET18 is required for the full enzymatic activity of ROS1 in active DNA demethylation. Sci. Rep. 6, 26443; doi: 10.1038/srep26443
8. Li Q., Wang X., Sun H., Zeng J., Cao Z., Li Y., and Qian W. (2015). Regulation of Active DNA Demethylation by a Methyl-CpG-Binding Domain Protein in Arabidopsis thaliana. PLoS Genet. 11, e1005210.
9. Qian W.*, Miki D.*, Lei M.*, Zhu X., Zhang H., Liu Y., Li Y., Lang Z., Wang J., Tang K., et al. (2014). Regulation of active DNA demethylation by an alpha-crystallin domain protein in Arabidopsis. Mol. Cell 55, 361-371. (*Contributed equally to this work)
10. Li Y.*, Cordoba-Canero D.*, Qian W.*, Zhu X., Tang K., Zhang H., Ariza R.R., Roldan-Arjona T., and Zhu J.K. (2015). An AP endonuclease functions in active DNA demethylation and gene imprinting in Arabidopsis. PLoS Genet. 11, e1004905. (*Contributed equally to this work)
11. Qian W.*, Miki D.*, Zhang H., Liu Y., Zhang X., Tang K., Kan Y., La H., Li X., Li S., et al. (2012). A histone acetyltransferase regulates active DNA demethylation in Arabidopsis. Science 336, 1445-1448. (*Contributed equally to this work)
12. Martinez-Macias M.I.*, Qian W.*, Miki D.*, Pontes O., Liu Y., Tang K., Liu R., Morales-Ruiz T., Ariza R.R., Roldan-Arjona T., et al. (2012). A DNA 3` phosphatase functions in active DNA demethylation in Arabidopsis. Mol. Cell 45, 357-370. (*Contributed equally to this work)
13. Mang H.G.*, Qian W.*, Zhu Y., Qian J., Kang H.G., Klessig D.F., and Hua J. (2012). Abscisic acid deficiency antagonizes high-temperature inhibition of disease resistance through enhancing nuclear accumulation of resistance proteins SNC1 and RPS4 in Arabidopsis. Plant Cell 24, 1271-1284. (*Contributed equally to this work)
Laboratory Introduction