1985-1989 Peking University, China B.S.
1989-1995 Peking University, China M.S. & Ph.D.
2008 - now Changjiang Scholar, Peking University
2001 - now, Professor, School of Life Sciences, Peking University
1999 - 2000 Senior Visiting Scholar , MCDB Department, Yale University, USA
1997 - 2001 Associate Professor, College of Life Sciences, Peking University
1995 - 1997 Lecturer, College of Life Sciences, Peking University
1995 - 1996 Visiting Scholar, John Innes Center, UK
2017－now Journal of Integrative Plant Biology, Editor
2004－now Science China Life Sciences, Editor
2009－now BMC Plant Biology, Associate Editor
2009－now PLOS Genetics, Associate Editor
2021－now PLOS Genetics, Section Editor: Plant Genetics
Associate Editor, BMC Plant Biology, 2009-
Associate Editor, PLoS Genetics , 2009-
Editor, Science China Life Science, 2004-
Sexual reproduction in higher plants is composed of multiple biological processes including gametogenesis, male-female interactions, fertilization and embryogenesis, which are under tight genetic regulation. Taking dicotyledous model plant Arabidopsis thaliana as research materials, we aim to dissect the molecular regulation mechanisms involved in plant reproduction by using combinations of genetic, biochemical and molecular biology approaches. We are mainly interested in three categories of the regulatory factors involved in plant reproduction: 1) receptor-like protein kinases/peptide signals-mediated signaling pathways; 2) factors regulating protein degradation and/or endomembrane trafficking; 3) transcription factors. We are also interested in developing new tools for genetic editing in plants.
Representative Peer-Reviewed Publications
1. Zhong S. et al., Qu L.-J.* (2022) RALF peptide signaling controls the polytubey block in Arabidopsis. Science 375: 290-296.
2. Li W. et al., Zhong S.*, Qu L.-J.* (2022) Lack of ethylene does not affect reproductive success and synergid cell death in Arabidopsis. Molecular Plants 15: 354-362.
3. Hou S. et al., Zhong S.*, Qu L.-J.* (2021) VPS18-regulated vesicle trafficking controls the secretion of pectin and its modifying enzyme during pollen tube growth in Arabidopsis. Plant Cell 33: 3042-3056.
4. Liu M. et al., Zhong S.*, Qu L.-J.* (2021) AtLURE1/PRK6-mediated signaling promotes conspecific micropylar pollen tube guidance. Plant Physiology 186: 865-873.
5. Ge Z., Dresselhaus T.,* Qu L.-J.* (2019) How CrRLK1L receptor complexes perceive RALF signals. Trends in Plant Science 24: 978-981.
6. Ge Z. et al., Qu L.-J.* (2019) LLG2/3 are co-receptors in BUPS/ANX-RALF signaling to regulate Arabidopsis pollen tube integrity. Current Biology 29: 3256-3265.
7. Zhong S. et al., Qu L.-J.* (2019) Cysteine-rich peptides promote interspecific genetic isolation in Arabidopsis. Science 364: eaau9564.
8. Zhong S., Qu L.-J.* 2019, Peptide/receptor-like kinase-mediated signaling involved in male-female interactions. Current Opinion in Plant Biology 51: 7-14.
9. Ge Z., Cheung A.Y.*, Qu L.-J.* (2019) Pollen tube integrity regulation in flowering plants: insights from molecular assemblies on the pollen tube surface. New Phytologist 222: 687-693.
10.Zhou H., Song Z., Zhong S., Zuo L., Qi Z.*, Qu L.-J.*, Lai L.* (2019) Mechanism of DNA-induced phase separation for transcriptional repressor VRN1. Angew. Chem. Int. Ed. 58: 4858-4862.
11.Ge Z. et al., Qu L.-J.* (2017) Arabidopsis pollen tube integrity and sperm release are regulated by RALF-mediated signaling. Science 358: 1596-1600.
12.Zhang J. et al., Qu L.-J.* (2017) Sperm cells are passive cargo of the pollen tube in plant fertilization. Nature Plants 3: 17079.
13.He S. et al., Qu L.-J.* (2017) A novel imprinted gene NUWA controls mitochondrial function in early seed development in Arabidopsis. PLOS Genetics 13(1): e1006553.
14.Hao L. et al., Qu L.-J.* (2016) AtVPS41-mediated endocytic pathway is essential for pollen tube-stigma interaction in Arabidopsis. Proceedings of the National Academy of Sciences, USA, 113: 6307-6312.
15.Hou Y. et al., Qu L.-J.* (2016) Maternal ENODLs are required for pollen tube reception in Arabidopsis. Current Biology 26: 2343-2350.
16.Wu Z. et al., Qu L.-J.* (2016) RNA-binding proteins RZ-1B and RZ-1C play critical roles in regulating pre-mRNA splicing and gene expression during development in Arabidopsis. Plant Cell 28: 55-73.
17.Zhang H., Lin X., Han Z., Qu L.-J.*, Chai J.* (2016) Crystal structure of PXY-TDIF complex reveals a conserved recognition mechanism among CLE peptide-receptor pairs. Cell Research 26: 543-555.
18.Zhang H., Lin X., Han Z., Wang J., Qu L.-J.*, Chai J.* (2016) SERK family receptor-like kinases function as a co-receptor with PXY for plant vascular development. Molecular Plant 9: 1406-1414.
19.Lin Q., Ogashi Y., Kato M., Tsuge T., Gu H., Qu L.-J.*, Aoyama T.* (2015) GLABRA2 targets basic Helix-loop-helix transcription factor genes to robustly suppress root hair development. Plant Cell 27: 2894-2906.
20.Qu L.-J.*, Li L., Lan Z., Dresselhaus T. (2015) Peptide signaling during the pollen tube journey and double fertilization. Journal of Experimental Botany 66 (17): 5139-5150.